This toxicological course with focus on hands-on training will, thanks to a number of companies engaged in the field of 3Rs, guide you through some of the validated OECD guidelines on local toxicity testing: 3 different skin models will be used to show practical applicability either in the field of skin irritation (EpiSkin, OECD TG 439), skin sensitization (Immunosearch) or skin permeability (Eurosafe).

An eye irritation model as developed by Mattek will be used to demonstrate its applicability for eye irritation detection (OECD TG 492).